I was a participant in the COSMOS trial (it was fun!) examining possible benefits for older folks from cocoa flavonoids and an ordinary multivitamin (they used Centrum Silver). While the cocoa extract had no effect on cognition, the multivitamin did–it actually improved cognition! (Cardiovascular events and cancer results are reported elsewhere). Here’s the summary:
Vitamins, minerals, and other bioactives in foods are important for normal brain function, and deficiencies in older adults may increase risk for cognitive decline. Dietary supplements are often recommended for cognitive protection, but supporting evidence is mixed. COSMOS investigators partnered with colleagues at Wake Forest University to test whether daily use of cocoa extract or a multivitamin for 3 years can reduce the risk of cognitive decline. The COSMOS-Mind sub-study enrolled 2,262 COSMOS participants aged 65 and older who completed annual telephone interviews to assess memory and thinking abilities. The investigators found that cocoa extract did not affect cognition. On the other hand, daily multivitamin use improved cognitive function. That is, participants assigned to the multivitamin group had higher cognitive test scores after 3 years than the participants assigned to the multivitamin-placebo group. The investigators estimated that taking the daily multivitamin slowed cognitive aging by approximately 60%, or the equivalent of 1.8 years over the 3 years of the study, but this finding requires confirmation in future research. “COSMOS-Mind provides the first evidence from a large randomized trial to show that regular use of a typical daily multivitamin may improve memory and thinking abilities in older adults,” noted COSMOS Co-Director Dr. Howard Sesso, who leads COSMOS with Dr. JoAnn Manson. However, the story continues to unfold as other investigators complete separate studies in COSMOS that dig more deeply into the effects of both cocoa extract and a multivitamin on different aspects of cognition and other aging-related outcomes.
I was ten when A Hard Day’s Night came out. It played for about a year at the Village Cinema, four blocks from my house in Greenwich Village. The Village Cinema was a little art house, and while my mother was not against dropping the kids at the movies (I was 10, my brother was 8) especially during the summer when it was hot and there was air conditioning, she preferred to do it at the Waverly or the Loews Sheraton (both larger, with a larger, more supervisory staff to make sure we wouldn’t be spirited away). I think she found the Village Cinema–what was called an “art house” in those days, a little skeevy. In any case, neither my mother nor my father was enthused by the idea of taking us themselves and spending two hours watching what they anticipated would be a standard teen-pop-star movie.
This post was written several years ago and published elsewhere.
Once I got reading under my belt, I couldn’t do enough of it–books, stories, cereal boxes, comic books. I gobbled up story like I was starving for it, initially uncritically, but fairly soon starting to think about why stories worked/didn’t work for me. In this I had a partner: my brother Clem. He and I amassed a comic book collection of perhaps 2000 well-worn, repeatedly read comics–most, but not all of them DC (the home of Superman and Batman). Clem and I haunted the smoke shop at the corner, where the new comics came in every… I think it was Tuesday… and conspired over which one of us would buy which. We took them home and read the them and then we talked over them. Clem, a far better artist than I will ever be, led the way in discussing the art. One of our favorite riding-on-the-subway games was to identify people who looked like they were drawn by specific artists.
My daughter is visiting, and wanted to watch the new Netflix version of Persuasion. She wanted me to watch Bridgerton when she was here over Christmas, but after 20 minutes of making increasingly acerbic comments I absented myself so as not to, as we say in my household, yuck her yum.